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Matchpoint Therapeutics closes $150M Series B led by Nextech Invest and Norwest to advance oral small molecule pipeline for autoimmune diseases.

PRIVATEOct 07, 2026

Amount Raised

$150 Million

Round Type

Series B

WatertownBiotechnologyTherapeutics

Investors

Digitalis VenturesSanofi VenturesAtlas VentureAccess BiotechnologyBOLD Longevity GrowthT1D FundBB BiotechInvusNorwest Venture PartnersNextech Invest

Description

Matchpoint Therapeutics announced the successful closing of a $150 million Series B financing round co-led by Nextech Invest and Norwest. New investors including Invus, BB Biotech, T1D Fund, and BOLD Longevity Growth participated alongside existing backers Access Biotechnology, Atlas Venture, and Sanofi Ventures. The proceeds will support clinical development of MPT-062, a first-in-class oral T cell modulator expected to begin trials in 2027, and advancement of the broader product pipeline. Board seats were granted to Kanishka Pothula from Nextech Invest and Brian Matesic from Norwest.

Company Information

Company

Matchpoint Therapeutics

Location

Watertown, Massachusetts, United States

About

Matchpoint Therapeutics is a biotechnology company based in Watertown, Massachusetts, pioneering the discovery of precision covalent medicines for autoimmune and inflammatory diseases. The company specializes in rationally designed covalent small molecules targeting historically hard-to-drug biovalidated targets. Its discovery platform integrates expertise in chemical biology, covalent chemistry, structure-based drug design, and computational sciences. The company has a focused pipeline of first-in-class programs and a discovery collaboration with Novartis.

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Funding Insights

What this usually means
Timeline to next round
Series B companies typically work for 15-20 months before raising new capital
Growth expectations
Series B companies are expected to scale rapidly and expand market reach

Matchpoint Therapeutics raised. Fundz records a round at a median of 3.6 minutes from the SEC filing, with the decision-maker attached.

145 of these a day, filtered to the companies you pick, with the decision-maker attached.

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Fundz is a real-time business intelligence platform powered by agentic AI that proactively delivers personalized daily signals, including funding rounds, executive changes, M&A activity, 13F institutional filings, SEC 8-K events, investor activity, and website modifications, based on each user's watchlist and ICP. A trusted data source at firms such as BlackRock, Oracle, Kleiner Perkins, LinkedIn, HubSpot, and Cloudflare, Fundz democratizes the institutional-grade intelligence that previously required a PitchBook or Bloomberg terminal. Features include FundzWatch™ for automated website change detection, Daily Briefing for AI-powered daily briefings, and unified cross-signal alerts across 281,000+ organizations. Developers and data teams can access these signals programmatically via the Fundz Funding Data API, with transparent published pricing.