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SynAct Pharma AB Appoints Mads Bjerregaard as Chief Business Officer

PRIVATESep 05, 2025

Position

Chief Business Officer

Company

SynAct Pharma

Mads Bjerregaard
LundBiotechnologyHealth Careresearch

Description

SynAct Pharma AB has appointed Mads Bjerregaard as its new Chief Business Officer, succeeding Jim Knight. This strategic move comes as SynAct is at a pivotal stage with its Phase 2b ADVANCE study for rheumatoid arthritis and aims to enhance commercial prospects.

Other recent leadership changes in research and Biotechnology

Executive moves at companies in the same sectors within 45 days, from Fundz verified event records.

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Company Information

Company

SynAct Pharma

Location

2 Scheelevaegen

Lund, Skåne County, Sweden

About

SynAct Pharma is a biotech company aiming at resolving inflammation by leveraging melanocortin biology. Our lead asset AP1189 is in phase 2 development for the treatment of rheumatoid arthritis. AP1189 is an immunomodulatory small molecule delivered as a once-daily tablet. The mode of action is selective melanocortin receptor type 1 and 3 agonism, making it first-in-class. Activation of these receptors results in reduced secretion of proinflammatory cytokines by neutrophils and in conversion of macrophages towards clearing away cellular debris in hyper-inflamed tissue – two effects that together induce resolution of inflammation. The Phase 2a BEGIN study in patients with rheumatoid arthritis reported very promising efficacy and safety results in November 2021 - next step is to open an IND with FDA to get advice on further development.

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