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4D Molecular Therapeutics Shares Promising Results from Phase 2b PRISM Wet AMD Study for Product 4D-150.

Feb 08, 2025
EmeryvilleBiotechnologyHealth CareMedicalGeneticsTherapeutics

Product Description

4D Molecular Therapeutics announced positive 52-week data from the Phase 2b study of 4D-150, focusing on its effectiveness for treating wet age-related macular degeneration. CEO David Kirn highlighted the potential of 4D-150 to be a foundational therapy for vascular retinal diseases.

Company Information

Company

4D Molecular Therapeutics

Location

Emeryville, California, United States

About

4DMT is a late-stage biotechnology company developing durable, disease-targeted genetic medicines designed to transform treatment paradigms and deliver long-lasting benefits to patients. Its lead candidate, 4D-150, aims to become a backbone therapy for blinding retinal vascular diseases by providing multi-year sustained delivery of anti-VEGF agents through a single intravitreal injection, with Phase 3 development underway for wet age-related macular degeneration and a second indication in diabetic macular edema. The company’s second candidate, 4D-710, is the first known genetic medicine to achieve successful aerosol-based delivery and expression of the CFTR transgene in the lungs of people with cystic fibrosis.

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