Spyre Therapeutics has priced a $275 million public offering of common stock at $18.50 per share, expected to close on October 15, 2025. Jefferies LLC and other firms are leading the offering.
Amount Raised
$275 Million
Round Type
Post-IPO Equity
Investors
Description
Spyre Therapeutics, Inc. announced the pricing of its underwritten public offering of 14,864,865 shares at $18.50 per share, expected to raise approximately $275 million. The offering's lead managers include Jefferies LLC and Stifel, Nicolaus & Company. The company has granted underwriters a 30-day option to purchase additional shares
Quick answer
Spyre Therapeutics raised $275 Million in a Post-IPO Equity round, dated October 14, 2025. Investors: Wedbush Securities Inc., Stifel, Nicolaus & Company, Incorporated, Leerink Partners LLC, TD Securities (USA) LLC and Jefferies LLC. Spyre Therapeutics is based in Waltham, Massachusetts, United States.
- How much did Spyre Therapeutics raise?
- Spyre Therapeutics raised $275 Million in a Post-IPO Equity round on October 14, 2025.
- Who invested in Spyre Therapeutics?
- Wedbush Securities Inc., Stifel, Nicolaus & Company, Incorporated, Leerink Partners LLC, TD Securities (USA) LLC and Jefferies LLC are named as investors in this round.
- What does Spyre Therapeutics do?
- Spyre Therapeutics is a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease (“IBD”) and rheumatic diseases.
- Where is Spyre Therapeutics based and how big is it?
- Spyre Therapeutics is based in Waltham, Massachusetts, United States. Fundz records about 112 employees.
- Who are the decision-makers at Spyre Therapeutics?
- Fundz holds 1 contact at Spyre Therapeutics. Names and contact details are shown to Fundz members.
Source: Fundz verified event record.
Who else raised in Therapeutics and Biotechnology around the same time
Companies in the same sectors as Spyre Therapeutics that raised within 45 days of this round, from Fundz verified event records.
- Azora Therapeutics, Inc. (DE) raised $4.3M on November 28, 2025.
- SymPhysis Medical raised $1.3M (Grant) on November 26, 2025.
- Verrica raised $50M on November 25, 2025.
- FibroBiologics raised $1.5M on November 24, 2025.
- MindImmune Therapeutics raised $10M (Series A) on November 24, 2025.
- BeyondSpring raised $2M (Funding Round) on November 21, 2025.
Who to call at Spyre Therapeutics, and when
A new round usually means Spyre Therapeutics is about to hire and buy. The teams that reach out first get the meeting.
- An alert the day Spyre Therapeutics raises, hires an executive or expands, scored against what you sell
- The decision-makers there, with verified emails
- Who you already know at Spyre Therapeutics, from your own LinkedIn network
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Related People
Spyre Therapeutics raised. Fundz records a round at a median of 3.6 minutes from the SEC filing, with the decision-maker attached.
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