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Spyre Therapeutics announces the pricing of a $350 million public offering of common stock, with plans to advance research and development across several therapeutic areas.

PUBLIC · SYREOct 06, 2026

Amount Raised

$350 Million

Round Type

Post-IPO Equity

BengaluruBiotechnologyHealth CareTherapeutics

Investors

StifelLeerink PartnersTD CowenJefferies

Description

Spyre Therapeutics has priced its public offering at $85.00 per share, expected to raise approximately $350 million in gross proceeds. The funds will support ongoing programs in Gastroenterology, Rheumatology, and Dermatology. The offering is set to close by October 7, 2026. Jefferies, TD Cowen, and others are managing the offering.

Company Information

Company

Spyre Therapeutics

Location

Bengaluru, Karnataka, India

About

Spyre Therapeutics is a clinical-stage biotechnology company pioneering long-acting antibodies and antibody combinations to redefine the standard of care for inflammatory bowel disease (“IBD”) and rheumatic diseases. Spyre's pipeline includes investigational extended half-life antibodies targeting α4β7, TL1A, and IL-23.

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Spyre Therapeutics raised. Fundz records a round at a median of 3.6 minutes from the SEC filing, with the decision-maker attached.

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