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Pinetree Therapeutics has raised $47 million in an oversubscribed Series B round to advance next-generation protein degraders in oncology.

PRIVATEOct 29, 2025

Amount Raised

$47 Million

Round Type

Series B

CambridgeBiotechnologyHealth CareScience And Engineering

Investors

Gauss Capital ManagementSTIC Ventures

Description

Pinetree Therapeutics has successfully completed an oversubscribed Series B funding round, raising $47 million. The capital will be utilized to advance their next-generation protein degraders aimed at treating oncology patients. This significant investment underscores the growing interest in innovative cancer therapies. The funding round was led by prominent investors in the biotech sector.

Quick answer

PineTree Therapeutics raised $47 Million in a Series B round, dated October 29, 2025. Investors: Gauss Capital Management and STIC Ventures. PineTree Therapeutics is based in Cambridge, Massachusetts, United States.

How much did PineTree Therapeutics raise?
PineTree Therapeutics raised $47 Million in a Series B round on October 29, 2025.
Who invested in PineTree Therapeutics?
Gauss Capital Management and STIC Ventures are named as investors in this round.
What does PineTree Therapeutics do?
Pinetree Therapeutics, based in Cambridge, MA, is a preclinical-stage biotech company developing next-generation targeted protein degraders (TPDs) to overcome drug resistance and tumor recurrence in oncology, with..
Where is PineTree Therapeutics based and how big is it?
PineTree Therapeutics is based in Cambridge, Massachusetts, United States. Fundz records about 36 employees.
Who are the decision-makers at PineTree Therapeutics?
Fundz holds 1 contact at PineTree Therapeutics, including the CEO/Founder. Names and contact details are shown to Fundz members.

Source: Fundz verified event record.

Who else raised in Science And Engineering and Biotechnology around the same time

Companies in the same sectors as PineTree Therapeutics that raised within 45 days of this round, from Fundz verified event records.

  • Enveric Biosciences raised $107K on December 12, 2025.
  • Aprea Therapeutics raised $3.1M on December 10, 2025.
  • TandemAI raised $22M (Series A) on November 14, 2025.
  • Equillium raised $50M (Funding Round) on November 13, 2025.
  • Electra Therapeutics raised $183M (Series C) on October 22, 2025.
  • RedHill Biopharma Ltd raised $4M (Corporate Round) on October 20, 2025.

Who to call at PineTree Therapeutics, and when

A new round usually means PineTree Therapeutics is about to hire and buy. The teams that reach out first get the meeting.

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Company Information

Company

PineTree Therapeutics

Location

767 Concord Ave

Cambridge, Massachusetts, United States

About

Pinetree Therapeutics, based in Cambridge, MA, is a preclinical-stage biotech company developing next-generation targeted protein degraders (TPDs) to overcome drug resistance and tumor recurrence in oncology, with applications in inflammation and immunology. Its proprietary AbReptor™ platform enables selective degradation of membrane-bound and extracellular proteins, offering a differentiated mechanism of action and durable therapeutic benefit. Pinetree is also advancing trispecific degraders and ADC-integrated platforms, and has entered strategic partnerships, including a licensing agreement with AstraZeneca.

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Related People

1 contact
Verified contactsHo-Juhn S., CEO/Founder hidden hiddenSee plans and pricing
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Funding Insights

What this usually means
Timeline to next round
Series B companies typically work for 15-20 months before raising new capital
Growth expectations
Series B companies are expected to scale rapidly and expand market reach

PineTree Therapeutics raised. Fundz records a round at a median of 3.6 minutes from the SEC filing, with the decision-maker attached.

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