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Diagonal Therapeutics secures $125M in Series B funding to advance DIAG723, targeting rare diseases HHT and PAH, led by Sanofi Ventures.

PRIVATEJan 08, 2026

Amount Raised

$125 Million

Round Type

Series B

CambridgeBiotechnologyHealth Care

Investors

James Henderson InvestorsSanofi Ventures

Description

Diagonal Therapeutics has raised $125 million in a Series B financing round to advance its DIAG723 drug for hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension. The funding, led by Sanofi Ventures, will support the company's first-in-human trial. Diagonal aims to address critical gaps in treatment for these rare diseases. CEO Alex Lugovskoy highlighted the potential of DIAG723 in reversing disease pathology.

Quick answer

Diagonal Therapeutics raised $125 Million in a Series B round, dated January 8, 2026. Investors: James Henderson Investors and Sanofi Ventures. Diagonal Therapeutics is based in Cambridge, Massachusetts, United States.

How much did Diagonal Therapeutics raise?
Diagonal Therapeutics raised $125 Million in a Series B round on January 8, 2026.
Who invested in Diagonal Therapeutics?
James Henderson Investors and Sanofi Ventures are named as investors in this round.
What does Diagonal Therapeutics do?
Diagonal Therapeutics is a biotech company pioneering a new approach to discovering and developing agonist antibodies.
Where is Diagonal Therapeutics based and how big is it?
Diagonal Therapeutics is based in Cambridge, Massachusetts, United States. Fundz records about 28 employees.
Who are the decision-makers at Diagonal Therapeutics?
Fundz holds 1 contact at Diagonal Therapeutics. Names and contact details are shown to Fundz members.

Source: Fundz verified event record.

Who else raised in Biotechnology and Health Care around the same time

Companies in the same sectors as Diagonal Therapeutics that raised within 45 days of this round, from Fundz verified event records.

  • QSTEM raised $1.5M (Seed) on February 20, 2026.
  • Altesa raised $75M (Series B) on February 19, 2026.
  • Lario Therapeutics raised $2.4M (Grant) on February 19, 2026.
  • Epetōme raised an undisclosed amount on February 19, 2026.
  • Elumn8 Medical raised an undisclosed amount (Series C) on February 18, 2026.
  • Faeth Therapeutics raised $200M (Post-IPO Equity) on February 18, 2026.

Who to call at Diagonal Therapeutics, and when

A new round usually means Diagonal Therapeutics is about to hire and buy. The teams that reach out first get the meeting.

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Company Information

Company

Diagonal Therapeutics

Location

Cambridge, Massachusetts, United States

About

Diagonal Therapeutics is a biotech company pioneering a new approach to discovering and developing agonist antibodies. The Company's DIAGONAL platform combines proprietary computational and experimental techniques to overcome historical challenges associated with agonist antibody drug discovery. Diagonal's emerging pipeline – discovered using the DIAGONAL platform – has the potential to deliver life-changing therapies to patients including therapies for hereditary hemorrhagic telangiectasia and pulmonary arterial hypertension. For more information, please visit www.diagonaltx.com.

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Funding Insights

What this usually means
Timeline to next round
Series B companies typically work for 15-20 months before raising new capital
Growth expectations
Series B companies are expected to scale rapidly and expand market reach

Diagonal Therapeutics raised. Fundz records a round at a median of 3.6 minutes from the SEC filing, with the decision-maker attached.

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