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City Therapeutics secures $99.5 million in Series B funding to enhance its RNAi pipeline, led by prominent investors. The funds will advance its lead asset CITY-FXI and support business development activities.

PUBLIC · CTYJun 08, 2026

Amount Raised

$99.5 Million

Round Type

Series B

CambridgeBiotechnologyHealth CareTherapeutics

Description

City Therapeutics has raised $99.5 million in a Series B funding round to further develop RNA interference medicines. The funds will be directed towards advancing CITY-FXI, aimed at preventing blood clots, alongside enhancements to its RNAi engineering platform. City is also working on therapies for Stargardt disease and other undisclosed targets. This financing underscores the company's progress in leading next-gen RNAi-based medicines.

Quick answer

City Therapeutics raised $99.5 Million in a Series B round, dated June 8, 2026. City Therapeutics is based in Cambridge, Massachusetts, United States.

How much did City Therapeutics raise?
City Therapeutics raised $99.5 Million in a Series B round on June 8, 2026.
What does City Therapeutics do?
City Therapeutics is a biopharmaceutical company harnessing next-generation engineering of RNAi trigger molecules to improve and expand the reach of RNAi-based medicines.
Where is City Therapeutics based and how big is it?
City Therapeutics is based in Cambridge, Massachusetts, United States. Fundz records about 75 employees.
Who are the decision-makers at City Therapeutics?
Fundz holds 1 contact at City Therapeutics. Names and contact details are shown to Fundz members.

Source: Fundz verified event record.

Who else raised in Therapeutics and Biotechnology around the same time

Companies in the same sectors as City Therapeutics that raised within 45 days of this round, from Fundz verified event records.

  • Scancell Holdings PLC raised $39M (Post-IPO Equity) on July 23, 2026.
  • Transcripta Bio raised $24M (Series A) on July 22, 2026.
  • Mentari Therapeutics raised $200M (Post-IPO Equity) on July 22, 2026.
  • Tikva Allocell Pte. Ltd raised $8M (Series A) on July 22, 2026.
  • Immitra Bio raised $2.5M (Pre-Seed) on July 21, 2026.
  • Kaveri Therapeutics raised $1.6M (Seed) on July 21, 2026.

Who to call at City Therapeutics, and when

A new round usually means City Therapeutics is about to hire and buy. The teams that reach out first get the meeting.

  • An alert the day City Therapeutics raises, hires an executive or expands, scored against what you sell
  • The decision-makers there, with verified emails
  • Who you already know at City Therapeutics, from your own LinkedIn network

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Company Information

Company

City Therapeutics

Location

399 Binney St

Cambridge, Massachusetts, United States

About

City Therapeutics is a biopharmaceutical company harnessing next-generation engineering of RNAi trigger molecules to improve and expand the reach of RNAi-based medicines. The company is building a pipeline of innovative RNAi therapeutics to make a significant impact for patients across multiple therapeutic areas. Co-founded by pioneering executives and scientists in RNAi, City Therapeutics is based in Cambridge, MA, and has raised $135 million from leading life sciences investors.

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Fundz sees it the moment City Therapeutics raises, hires an exec or expands, usually minutes after it happens, and tells you who to reach.

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Funding Insights

What this usually means
Timeline to next round
Series B companies typically work for 15-20 months before raising new capital
Growth expectations
Series B companies are expected to scale rapidly and expand market reach

City Therapeutics raised. Fundz records a round at a median of 3.6 minutes from the SEC filing, with the decision-maker attached.

145 of these a day, filtered to the companies you pick, with the decision-maker attached.

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Fundz is a real-time business intelligence platform powered by agentic AI that proactively delivers personalized daily signals, including funding rounds, executive changes, M&A activity, 13F institutional filings, SEC 8-K events, investor activity, and website modifications, based on each user's watchlist and ICP. A trusted data source at firms such as BlackRock, Oracle, Kleiner Perkins, LinkedIn, HubSpot, and Cloudflare, Fundz democratizes the institutional-grade intelligence that previously required a PitchBook or Bloomberg terminal. Features include Daily Briefing for AI-powered daily briefings, and unified cross-signal alerts across 281,000+ organizations. Developers and data teams can access these signals programmatically via the Fundz Funding Data API, with transparent published pricing.