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Anacalypsis Therapeutics secures pre-seed funding led by Metavallon VC's Brain Gain Fund to advance AT001, a stapled peptide for LRRK2-associated Parkinson's disease.

PRIVATESep 21, 2026about 10 hours ago

Round Type

Seed

GreeceBiotechnologyHealth CareTherapeutics

Investors

Metavallon Vc

Description

Greece-based Anacalypsis Therapeutics has raised a pre-seed financing round led by Metavallon VC through its Brain Gain Fund to advance AT001, a stapled peptide targeting the LRRK2–FADD protein-protein interaction for Parkinson's disease. The funding will support a key in vivo efficacy study of AT001 in preclinical models and establish proof of concept. Proceeds will also fund Anacalypsis' broader pipeline of therapeutic and biomarker programs. The company was founded around research showing that pathogenic LRRK2 can engage the death-adaptor protein FADD and activate neuronal cell-death signaling.

Company Information

Company

Anacalypsis Therapeutics

Location

Greece

About

Anacalypsis Therapeutics is a Greece-based biotech startup developing AT001, a stapled peptide targeting the LRRK2–FADD protein-protein interaction for treating Parkinson's disease. The company was founded around research from the Biomedical Research Foundation of the Academy of Athens led by Hardy J. Rideout. Unlike kinase inhibitor approaches, Anacalypsis's strategy aims to disrupt protein-protein interactions rather than inhibit LRRK2 kinase activity directly. The company is initially focusing on Parkinson's disease associated with pathogenic LRRK2 variants.

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