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Alphyn Biologics Secures $25M in Oversubscribed Series B to Enhance Dermatology Pipeline.

PRIVATEDec 12, 2025

Amount Raised

$25 Million

Round Type

Series B

AnnapolisBiotechnologyHealthcare

Investors

Angel Physicians FundSerial Stage Venture PartnersQCA Investment Group

Description

Alphyn Biologics, Inc. has closed its $25 million oversubscribed Series B financing round. The funds will support the Phase 2b clinical trial of Zabalafin Hydrogel for atopic dermatitis and initiate a Phase 2 program for molluscum contagiosum. The financing was led by QCA Investment Group, with participation from existing and new investors

Quick answer

Alphyn Biologics raised $25 Million in a Series B round, dated December 12, 2025. Investors: Angel Physicians Fund, Serial Stage Venture Partners and QCA Investment Group. Alphyn Biologics is based in Annapolis, Maryland, United States.

How much did Alphyn Biologics raise?
Alphyn Biologics raised $25 Million in a Series B round on December 12, 2025.
Who invested in Alphyn Biologics?
Angel Physicians Fund, Serial Stage Venture Partners and QCA Investment Group are named as investors in this round.
What does Alphyn Biologics do?
Alphyn Biologics is a clinical-stage dermatology company developing first-in-class multi-target therapeutics for severe and prevalent skin diseases based on its AB-101 platform.
Where is Alphyn Biologics based and how big is it?
Alphyn Biologics is based in Annapolis, Maryland, United States. Fundz records about 4 employees.
Who are the decision-makers at Alphyn Biologics?
Fundz holds 1 contact at Alphyn Biologics, including the President. Names and contact details are shown to Fundz members.

Source: Fundz verified event record.

Who else raised in Healthcare and Biotechnology around the same time

Companies in the same sectors as Alphyn Biologics that raised within 45 days of this round, from Fundz verified event records.

  • Ocugen raised $23M (Post-IPO Equity) on January 26, 2026.
  • Novabay raised $134M on January 16, 2026.
  • Os Therapies raised $3.5M on January 14, 2026.
  • Route 92 Medical raised $50M on January 13, 2026.
  • Tessera Defense & Homeland Security Inc. raised $3.3M on January 13, 2026.
  • Parabilis Medicines raised $305M (Series F) on January 8, 2026.

Who to call at Alphyn Biologics, and when

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Company Information

Company

Alphyn Biologics

Location

3724A THOMAS POINT ROAD

Annapolis, Maryland, United States

About

Alphyn Biologics is a clinical-stage dermatology company developing first-in-class multi-target therapeutics for severe and prevalent skin diseases based on its AB-101 platform. Its lead product candidate, AB-101a, is a topical treatment for atopic dermatitis (AD), the most common form of eczema, currently in a Phase 2a clinical trial. AB-101a has demonstrated a strong safety profile and is in development to uniquely target AD's bacterial and immune system components, making it ideal for treating infected and non-infected AD. Alphyn's AB-101 platform has multiple bioactive compounds and, therefore, multiple mechanisms of action to support a robust pipeline of dermatologic therapeutics with potential safety, efficacy, and regulatory marketing authorization advantages. Alphyn is based in Annapolis, Maryland, and Cincinnati, Ohio, and has a wholly owned subsidiary in Australia. We became operational in 2020 and have raised approximately $6.7 million.

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Related People

1 contact
Verified contactsSteven P., President hidden hiddenSee plans and pricing
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Funding Insights

What this usually means
Timeline to next round
Series B companies typically work for 15-20 months before raising new capital
Growth expectations
Series B companies are expected to scale rapidly and expand market reach

Alphyn Biologics raised. Fundz records a round at a median of 3.6 minutes from the SEC filing, with the decision-maker attached.

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