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Affinia Therapeutics secured $40 million in Series C financing, led by New Enterprise Associates, to advance AFTX-201 for BAG3 dilated cardiomyopathy.

PRIVATEOct 07, 2025

Amount Raised

$40 Million

Round Type

Series C

WalthamOtherBiotechnologyHealth Careresearch

Investors

GVEli Lilly & CompanyAlexandria Venture Investments, LLCAtlas VentureAvidity PartnersF PrimeMass General Brigham VenturesPerceptive AdvisorsNew Enterprise Associates

Description

Affinia Therapeutics has closed a $40 million Series C financing led by New Enterprise Associates, with participation from Eli Lilly & Company and other existing investors. The funds will support IND submission and clinical activities for AFTX-201, targeting BAG3 dilated cardiomyopathy. Affinia aims to submit an Investigational New Drug application by Q4 2025 and start a Phase 1/2 trial in Q1 2026. The financing also enables further development within Affinia's gene therapy pipeline.

Quick answer

Affinia Therapeutics raised $40 Million in a Series C round, dated October 7, 2025. Investors: GV, Eli Lilly & Company, Alexandria Venture Investments, LLC, Atlas Venture, Avidity Partners, F Prime, Mass General Brigham Ventures and Perceptive Advisors. Affinia Therapeutics is based in Waltham, Massachusetts, United States.

How much did Affinia Therapeutics raise?
Affinia Therapeutics raised $40 Million in a Series C round on October 7, 2025.
Who invested in Affinia Therapeutics?
GV, Eli Lilly & Company, Alexandria Venture Investments, LLC, Atlas Venture, Avidity Partners, F Prime, Mass General Brigham Ventures and Perceptive Advisors are named as investors in this round.
What does Affinia Therapeutics do?
Affinia Therapeutics is pioneering a shift to a new class of rationally designed gene therapies that treat rare and prevalent diseases.
Where is Affinia Therapeutics based and how big is it?
Affinia Therapeutics is based in Waltham, Massachusetts, United States. Fundz records about 49 employees.
Who are the decision-makers at Affinia Therapeutics?
Fundz holds 2 contacts at Affinia Therapeutics, including the Chief Executive Officer. Names and contact details are shown to Fundz members.

Source: Fundz verified event record.

Who else raised in research and Biotechnology around the same time

Companies in the same sectors as Affinia Therapeutics that raised within 45 days of this round, from Fundz verified event records.

  • Brainstorm Cell Therapeutics raised $155K (Convertible Note) on November 6, 2025.
  • Hepta raised $6.7M (Seed) on November 5, 2025.
  • AAVantgarde Bio raised $141M (Series B) on November 3, 2025.
  • Grail raised $325M (Post-IPO Equity) on October 20, 2025.
  • Cyclana Bio raised $6.7M (Pre-Seed) on October 20, 2025.
  • Faeth Therapeutics raised $25M (Funding Round) on October 20, 2025.

Who to call at Affinia Therapeutics, and when

A new round usually means Affinia Therapeutics is about to hire and buy. The teams that reach out first get the meeting.

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Company Information

Company

Affinia Therapeutics

Location

43 Foundry Ave

Waltham, Massachusetts, United States

About

Affinia Therapeutics is pioneering a shift to a new class of rationally designed gene therapies that treat rare and prevalent diseases. Affinia Therapeutics’ pipeline of first-in-class or best-in-class product candidates in cardiovascular and neurological diseases leverages its proprietary next-generation capsids, payloads, or manufacturing approaches and have shown efficacy, safety, and differentiation in relevant animal models.

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Related People

2 contacts
Verified contactsRick M., Chief Executive Officer hiddenSee plans and pricing
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Affinia Therapeutics raised. Fundz records a round at a median of 3.6 minutes from the SEC filing, with the decision-maker attached.

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