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Synedgen Signs $119 Million Contract with BARDA for MIIST305 Development
Jul 03, 2025•12 months ago
Contract Type
contract
ClaremontHealthcareHealth Care
Description
Synedgen, Inc. has executed a contract with the Biomedical Advanced Research Agency (BARDA) valued at up to $119 million. This agreement is focused on the development of MIIST305, a medical countermeasure for gastrointestinal acute radiation syndrome, under the leadership of Dr. Laura Saward as CEO.
Company Information
Company
Synedgen
Location
1420 N. CLAREMONT BOULEVARD
Claremont, California, United States
About
Synedgen, Inc. is a biotechnology company developing Multivalent Innate Immune Signaling Target (MIIST) therapeutics that modulate and enhance the innate immune system. The company’s lead development candidate is MIIST305, an oral, glycocalyx targeted induction and maintenance therapy for ulcerative colitis (UC). With US Government support, MIIST305 is also being developed in parallel as a medical countermeasure (MCM) for gastrointestinal acute radiation syndrome (GI-ARS). MIIST technology has been validated with clinical trials in partnered programs and extensively peer-reviewed through twenty-two (22) National Institutes of Health grants and Department of Defense contracts. Synedgen has an in-house GMP manufacturing facility.