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Orum Therapeutics and Vertex Pharmaceuticals Enter into Multi-Target License and Option Agreement

Jul 16, 2024almost 2 years ago

Contract Type

agreement

Boston

Description

Orum Therapeutics has announced a global, multi-target license and option agreement with Vertex Pharmaceuticals. Under this agreement, Vertex has been granted rights to conduct research using Orum’s Dual-Precision Targeted Protein Degradation (TPD²®) technology for the discovery of novel targeted conditioning agents for use with gene editing. Orum will receive an upfront payment of $15 million and is eligible to receive additional option payments and milestones potentially totaling up to $310 million per target for up to three targets, as well as tiered royalties on potential future global annual net sales.

Company Information

Company

Orum Therapeutics

Location

Boston, Massachusetts, United States

About

Orum Therapeutics is pioneering the development of tumor-directed targeted protein degraders to improve the treatment of cancer. The company’s neoDegraders are novel, proprietary payloads for targeted protein degradation and its Antibody neoDegrader Conjugate (AnDC) platform generates first-in-class antibody drug conjugates. The first therapeutic candidates from the AnDC platform are in development for the treatment of solid tumors and hematologic cancers. Orum is located in Cambridge, Massachusetts, U.S., and Daejeon, Korea. For more information, visit www.orumrx.com.

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