KeifeRx, LLC, is an emerging clinical-stage biopharmaceutical company developing a pipeline of optimized, low dose, orally delivered tyrosine kinase inhibitors (TKIs) for the treatment of multiple neurodegenerative diseases. KeifeRx's optimized TKIs are designed to penetrate the brain, induce autophagy, and treat neurodegenerative diseases through the bulk disposal of disease-causing toxic proteins. KeifeRx's clinical pipeline is led by Nilotinib BE, an optimized, lower dose formulation of nilotinib delivered as an oral capsule, which the company is advancing in a multicenter Phase 3 clinical trial in early Alzheimer's disease (NILEAD). KeifeRx has rights to cross reference the INDs for the clinical trials of nilotinib conducted at Georgetown University. Georgetown University has completed a Phase 2 clinical trial in Parkinson's disease and is currently conducting clinical trials in Lewy body dementia (Phase 2) and Huntington's disease (Phase 1b). In addition to Nilotinib, KeifeRx's TKI portfolio includes an optimized oral dose of Bosutinib, which is the subject of a Phase 2 clinical program in Lewy body dementia at Georgetown, and Gutinib, which is currently undergoing optimizing and IND enabling studies at Georgetown involving four separate formulations. Georgetown University owns several issued patents and pending patent applications on the underlying technology that relates to the use of TKIs for the treatment of neurodegenerative diseases with Charbel Moussa, MBBS, Ph.D., as an inventor. KeifeRx has an exclusive option to license the intellectual property from Georgetown University. For more information on KeifeRx, please visit https://www.keiferx.com.