US Startup Funding Rounds: September 21, 2026 – September 27, 2026
25 US venture rounds closed between September 21, 2026 and September 27, 2026, led by Island at $400M (Series F).
Every round below is a named venture round by a US-headquartered company, sourced from SEC filings and verified announcements. Investment funds, IPOs, post-IPO placements and valuation-only reports are excluded.
| Company | Location | Amount | Round | Date | What they do |
|---|---|---|---|---|---|
| Island | Dallas, Texas | $400M | Series F | September 24, 2026 | What if the enterprise had complete control over the browser? What would it mean for security, for productivity, for work itself? Introducing Islan… |
| Enveda Therapeutics, Inc. | Boulder, Colorado | $311M | Series E | September 23, 2026 | Enveda Biosciences is a biotechnology company building the first high-resolution chemical map of the natural world to tackle the toughest problems in … |
| Precision Neuroscience | NEW YORK, New York | $250M | Series D | September 24, 2026 | Precision Neuroscience is working to provide breakthrough treatments for the millions of people worldwide suffering from neurological illnesses. The c… |
| eMed | Miami, Florida | $200M | Series A | September 21, 2026 | eMed is a Miami-based digital healthcare company that uses artificial intelligence to reshape employee wellness and expand healthcare access. The star… |
| Hubble Network | Seattle, Washington | $200M | Series C | September 23, 2026 | Hubble Network is the world’s first satellite-powered Bluetooth network, enabling Bluetooth devices to connect directly to orbit. The company focuses … |
| Rightway | — | $155M | Series E | September 24, 2026 | Rightway is the leader in driving healthcare value for everyone, everywhere. Its care navigation and PBM platforms guide over one million members to t… |
| Vessl AI | San Francisco, California | $150M | Series C | September 23, 2026 | VESSL AI provides an end-to-end MLOps platform that enables high-performance ML teams to build, train, and deploy models faster at scale. |
| Numeral | San Francisco, California | $100M | Series C | September 23, 2026 | Numeral, founded in 2023 and based in San Francisco, handles the intricacies of sales tax compliance for both ecommerce and SaaS companies, providing … |
| Go.AI™ | Chicago, Illinois | $85M | Series A | September 22, 2026 | Go.AI™ is the leading provider of on-premises, examiner-ready AI infrastructure tailored for regulated industries. The company focuses on delivering i… |
| Watney | — | $80M | Series A | September 23, 2026 | Watney develops dexterous robots for data center operations, focusing on automating physical tasks like cable swaps and server restarts. The company h… |
| Ema | San Francisco, California | $77M | Series B | September 23, 2026 | Ema is building the next generation AI technology to empower every employee in the enterprise to be their most creative and productive. Our proprietar… |
| BigHat Biosciences | SAN MATEO, California | $75.1M | Series C | September 26, 2026 | BigHat’s mission is to improve human health by making it far easier to design advanced, next-generation antibody therapeutics. Our AI-enabled experim… |
| Firecrawl | San Francisco, California | $75M | Series B | September 22, 2026 | Firecrawl is the web data toolkit for AI. Built for developers and AI teams, Firecrawl's full suite of tools for crawling, searching, and extracting w… |
| BigHat Biosciences | SAN MATEO, California | $75M | Series C | September 24, 2026 | BigHat’s mission is to improve human health by making it far easier to design advanced, next-generation antibody therapeutics. Our AI-enabled experim… |
| Warp | Los Angeles, California | $60M | Series B | September 26, 2026 | Warp empowers logistics, supply chain, and operations leaders to reduce freight costs, accelerate delivery timelines, and gain complete visibility, al… |
| Ande | New York, New York | $52M | Seed | September 22, 2026 | Ande is an AI-native network for corporate entertainment that aims to centralize and streamline the booking and expense management process for enterpr… |
| Moir | Palo Alto, California | $50M | Seed | September 21, 2026 | Moir is an identity verification company founded by an ex-Google and xAI staffer aimed at combating deepfakes and helping people verify their identiti… |
| AvenCell Therapeutics | Cambridge, Massachusetts | $47M | Series C | September 27, 2026 | AvenCell Therapeutics, Inc. is a leading clinical-stage cell therapy company that focuses on advancing autologous and allogeneic switchable CAR-T cell… |
| HIFI | New York, New York | $37M | Series A | September 24, 2026 | HIFI is the stablecoin infrastructure company that focuses on integrating traditional banking systems with blockchain technology for improved market o… |
| Baselayer | New York, New York | $35M | Series A | September 22, 2026 | Baselayer is an innovative B2B platform utilizing proprietary artificial intelligence technology to reduce fraud, automate business onboarding for SMB… |
| Outmarket | San Francisco, California | $34.5M | Series B | September 25, 2026 | Outmarket is the #1 AI platform for insurance, designed to empower agencies to scale their business without increasing headcount. The platform focuses… |
| Catena Labs | Boston, Massachusetts | $30M | Series A | September 21, 2026 | Catena Labs is building the first AI-native financial institution to provide the financial infrastructure and services AI systems need to conduct comm… |
| PicoJool | Palo Alto, California | $27.5M | Series A | September 24, 2026 | PicoJool Inc. is developing next-generation optical chips and modules for high-bandwidth, low-cost connectivity in hyperscale AI data centers. Founded… |
| Ramona Optics | DURHAM, North Carolina | $25M | Series A | September 22, 2026 | Ramona is the microscopy toolset for cutting-edge biological scientists. We unlock a new perspective on cellular-level research. Our advanced comp… |
| UltraSight | Boston, Massachusetts | $24M | Series B | September 23, 2026 | UltraSight is a leader in AI-guided cardiac workflows, focused on enhancing cardiac care through its Echosystem platform. The company aims to facilita… |
Frequently asked
Which US startups raised funding between September 21, 2026 and September 27, 2026?
25 US companies closed named venture rounds between September 21, 2026 and September 27, 2026, raising $2.66B in total. The largest were Island ($400M, Series F), Enveda Therapeutics, Inc. ($311M, Series E), Precision Neuroscience ($250M, Series D). Each round below is sourced from SEC filings and verified announcements, and excludes investment funds, IPOs and post-IPO placements.
What was the largest funding round of the week of September 21, 2026?
Island of Dallas, Texas raised $400M in a Series F round announced September 24, 2026. What if the enterprise had complete control over the browser? What would it mean for security, for productivity, for work itself? Introducing Island, the Ent It was the largest US venture round recorded in this window across 25 qualifying rounds.
How many US venture rounds closed this week?
25 named US venture rounds closed between September 21, 2026 and September 27, 2026, totalling $2.66B. This counts only rounds with a named series (Seed through Series G+) by US-headquartered operating companies. Investment funds raising vehicles, IPOs, post-IPO equity and valuation-only reports are excluded so the figures reflect genuine startup fundraising.
These are the rounds. Fundz gives you the people to call at each one — verified decision-makers matched to your market, the moment a round lands.
See plans